In this episode, Nick goes over the key characteristics of atherogenesis and the observations we have to explain. He also discusses the characterization of the disease and the transient behavior of coronary calcium scores (and therefore the difficulty of using them in the short term). Here’s a transcript of the episode.
Join us as we deep dive into the nuance of plaque progression with Nadir Ali. We get Nadir’s take on the endotoxemia hypothesis of plaque formation and atherogenesis, discuss the lipoprotein’s role in the body and immune system, and identify some key areas of focus for future research in holistic management of cardiovascular disease.